Which factor or combination makes replantation potentially not indicated for this patient?
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A 45-year-old immunosuppressed patient on high-dose methotrexate for rheumatoid arthritis has an avulsed lower premolar with advanced periodontal disease (grade III mobility on adjacent teeth, generalized 6mm+ pockets). Which factor or combination makes replantation potentially not indicated for this patient?
- A. Advanced age — patients over 40 have significantly reduced PDL regeneration capacity
- B. Severe periodontal disease combined with immunosuppression — both are listed contraindications
- C. The tooth is a premolar — the IADT only recommends replantation for anterior incisor teeth
- D. Methotrexate use alone — this medication completely prevents any periodontal healing response
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IADT: 'There are also individual situations when replantation is not indicated (eg, severe caries or periodontal disease, severe medical conditions such as immunosuppression).' Both conditions are present here, making replantation potentially not indicated. SOURCE — Fouad AF et al. IADT Avulsion Guidelines, Dent Traumatol 2020;36:331-342, Section 1
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